Solutions for cattle

Mastitis

Mastitis is the inflammation of the udder in dairy cattle, mainly caused by bacterial infection. Prevention and treatment of mastitis in these animals is key to producing healthy milk and minimising the symptoms associated with this clinical situation. Ubrolexin^® and Today^® are two products for the treatment of acute bacterial mastitis, whereas Ubrostar^® and Tomorrow^® are used to prevent mastitis during drying-off in dairy cattle at the end of their lactation period. Mamyzin^® is an effective injectable antimicrobial for the treatment of acute mastitis, and Metacam^® is used to reduce acute pain associated with this syndrome.

Indications	Brand Names	Active Ingredients
Mastitis	Mamyzin®	penethamate hydroiodide	Bovine mastitis caused by penicillin sensitive organisms.
Mastitis	Ubrostar® Benestermycin® Mamyzin® Secado	penethamate hydroiodide, framycetin sulphate, benethamine penicillin	For treatment of subclinical mastitis at drying off, and the prevention of new bacterial infections of the udder during the dry period in dairy cows, caused by bacteria susceptible to penicillin and framycetin.
Mastitis	Ubrolexin®	cefalexin, kanamycin combination	Treatment of clinical mastitis in lactating dairy cows for bacteria susceptible to the combination of cefalexin and kanamycin.
Mastitis	Today® Cefa-lak®	cephapirin sodium	Treatment of clinical mastitis in lactating dairy cows (US/Canada).
Mastitis	Tomorrow® Cefa-lak®	cephapirin benzathine	For treatment of subclinical mastitis at drying off, and the prevention of new bacterial infections of the udder during the dry period in dairy cows (US/Canada). For intramammary infusion into the dry cow (US only).

Pain and inflammatory disorders

Metacam^® is a non-steroidal ­anti-inflammatory drug (NSAID) and addresses the need for maintained profitability and the concern for animal welfare in animal production. Due to its long-acting nature and its outstanding efficacy in controlling inflammatory symptoms, Metacam^® helps to minimise losses from inflammation and maintain profitability. At the same time, Metacam^® effectively controls pain and supports the restoration of well-being in farm animals. The use of Metacam^® is convenient and inflicts minimal stress on animals due to its low-volume, one-shot dosage.

Metacam^® is licensed as adjunctive therapy in the treatment of mastitis in lactating cows. In most countries it is also indicated for use in calves affected by diarrhoea and in cattle suffering from respiratory disease.

Indications	Brand Names	Active Ingredients
Pain and inflammatory disorders	Metacam®	meloxicam	In cattle, Metacam® is used together with appropriate antibiotic therapy, to reduce clinical signs of disease, in acute respiratory infection It can be used in diarrhoea in combination with oral re-hydration therapy to reduce clinical signs of the disease in calves of over one week of age and young, non-lactating cattle. It can be used for the relief of post-operative pain following dehorning in calves and as supportive therapy in the treatment of acute mastitis in combination with antibiotics.

Infectious diseases

Bovine Viral Diarrhoea Virus (BVDV) is one of the major economically important cattle pathogens with a worldwide distribution. The disease caused by BVDV results in marked production losses in dairy and beef herds. Bovela^®is a vaccine that is designed to reduce some of the clinical signs typical for BVD, and to prevent the birth of so-called persistently infected animals caused by transplacental infection with BVDV. Vaccination with Bovela^® is expected to provide protection within the herd against the disease and against the circulation of the virus.

The Pyramid^® family of vaccines is providing a broad coverage against respiratory and reproductive diseases. The range consists of several antigen combinations suitable for the needs of the customer.

Indications	Brand Names	Active Ingredients
Cattle infectious diseases Respiratory and reproductive diseases in cattle	Pyramid® Presponse®	Several multivalent vaccine combinations including modified live viruses: bovine viral diarrhea (BVD) Types 1 and 2, infectious bovine rhinotracheitis (IBR), parainfluenza 3 (PI3) and bovine respiratory syncytial virus (BRSV), and bacteria: Pasteurella multocida,  Mannheimia haemolytica, L. canicola, L. grippotyphosa, L. hardjo, L. icterohaemmorrhagiae, and L. pomona.	For vaccination of healthy dairy or beef cattle as an aid in prevention of diseases caused by included antigens (US and Canada only).
Bovine Viral Diarrhoea	Bovela®	modified live BVDV *-1 strain, modified live BVDV *-2 strain   * Bovine Viral Diarrhoea Virus	Bovela® is used to protect cattle against BVD viral infection.