1948-1988: Going global

For Boehringer Ingelheim too, currency reforms and "economic miracles" provided a sound framework for continued growth. In 1955, the general economic boom that accompanied reconstruction saw a fourfold increase in the number of employees on that of 1939. New and highly effective pharmaceutical products were launched in the late 1950s, forming the basis of Boehringer Ingelheim’s research programme: agents for the treatment of respiratory, cardiovascular and gastrointestinal diseases.

The importance of foreign markets for a chemical/pharmaceutical concern was recognised by the founder's second son, Dr Ernst Boehringer. A home-based subsidiary was established in 1946 in Biberach an der Riss when the Thomae production unit was added to Boehringer Ingelheim’s two existing plants. The first foreign subsidiary, which was established in Vienna in 1948, was followed by more subsidiaries in Europe and overseas.

Following the death of Albert and Ernst Boehringer, Julius Liebrecht becomes Chairman of the Board in 1965. His son, Hubertus Liebrecht, joins the Board of Managing Directors in 1967 and is appointed Chairman in 1971. Albert’s son, Dr Wilhelm Boehringer, is also a member of the Board of Managing Directors, joining in 1967, and heads the Production and Technology division until his untimely death in 1975 at the age of 44.

From the 1950s until the late 1980s, Boehringer Ingelheim launches a number of important and innovative products onto the market, including the respiratory agents Alupent^® (1961), Bisolvon^® (1963), Berotec^® (1972), Atrovent^® (1975) and Berodual^® (1980).

Among its products used in the treatment of diseases of the cardiovascular system, Boehringer Ingelheim launches Catapresan^® (1966), which uses a new active principle in the treatment of hypertension. This is followed by Mexitil^® (1979), which is used in the treatment of arrhythmia.

In 1977, the company launches Asasantin^®, which is used in the treatment of thromboses and embolisms and combines the effects of Persantin^®(1959) and acetylsalicylic acid (ASS). This is followed in 1979 by the mucolytic agent Mucosolvan^®.

The launch of Actilyse^® in 1987 is, in two ways, a milestone for Boehringer Ingelheim. Not only is it the first thrombolytic treatment for acute heart attacks, but it is also Boehringer Ingelheim’s first proprietary product developed at its biopharmaceutical production site, which opened the year before.

Milestones during this period

1948: Founding of the first foreign subsidiary

Founding of the first foreign subsidiary: Bender & Co. GmbH in Vienna (now Regional Center Vienna).

1949: Beginning of partnership with J. R. Geigy AG

Thanks to the efforts of Robert Boehringer, 1949 sees the beginning of a long and successful partnership with the Swiss pharmaceutical company J. R. Geigy AG in Basel. Thomae gains the licence for the production and sole distribution of Geigy’s pharmaceutical specialities in Germany.

1949: Launch of Effortil^®, Vasculat^® and Visadron^®

Effortil^® (for improved circulation), Vasculat^® (a vasodilator) and Visadron^® (eye drops) are launched.

 

 

 

1951: Launch of Buscopan^®

1951 sees the launch of Buscopan^®, a spasmolytic agent of plant origin used in the treatment of gastrointestinal problems.

1952: Construction of company apartments in Biberach

The first company apartments are built in Biberach an der Riss.

1953: Founding of Boehringer Ingelheim Espana S. A.

Boehringer Ingelheim Espana S.A. is founded in Barcelona (Spain).

1955: Establishment of Animal Health division

The Animal Health division is set up as the company takes over Pfizer’s veterinary programme.

1955: Start of business operations in Japan

Business operations in Japan are expanded, although Nippon C. H. Boehringer Sohn Co. Ltd. is not founded until 1961.

1955: Founding of C. H. Boehringer Sohn SRL (Italy)

Business operations in Italy are expanded and C. H. Boehringer Sohn SRL is founded in Florence (Italy).

1956: Founding of Boehringer de Angeli Quimica e Farmaceutica Ltda. in Sao Paulo

Boehringer de Angeli Quimica e Farmaceutica Ltda. is founded in Sao Paulo (Brazil).

1957: Founding of Boehringer Ingelheim S. A. in Buenos Aires

Boehringer Ingelheim S. A. is founded in Buenos Aires (Argentina).

1958: Founding of C.H. Boehringer Sohn Ltd. in Toronto

C.H. Boehringer Sohn Ltd. is founded in Toronto (Canada).

1959: Launch of Persantin^®

Thomae carries out highly successful R&D activities culminating in the launch of Persantin^®, a product used in the treatment of coronary heart disease.

1959: First "International Days" in Ingelheim

First "International Days" in Ingelheim. Dr Ernst Boehringer launches the "International Days" to promote the appreciation and understanding of different cultures. With a variety of events and an art exhibition, this event, which celebrated its 50th anniversary in 2009, is a highlight of the town’s calendar.

 

1960: Launch of Silomat^®

1960 sees the launch of Silomat^®, a product used in the treatment of chesty coughs.

1960: Albert Boehringer jr. dies

The company founder’s eldest son, Albert Boehringer jr., dies on 11 February aged 69.

1960: 75th anniversary

Boehringer Ingelheim celebrates its 75th anniversary.

1961: Launch of Alupent^®

1961 sees the launch of Alupent^®, a respiratory agent that increases therapeutic competence for respiratory disease.

1961: Founding of Nippon Boehringer

The Japanese foreign subsidiary, Nippon Boehringer, is founded.

 

 

 

1961: Establishment of the Institute for Pharmaceutical Research in Vienna

The Institute for Pharmaceutical Research focusing on virology and pharmacology is established in Vienna.

1962: Founding of Mexicana de Alcaloides S. A. de C. V. in Orizaba

Mexicana de Alcaloides S. A. de C. V. is founded in Orizaba (Mexico).

1962: Founding of Boehringer Ingelheim Limited in Bracknell

Boehringer Ingelheim Limited is founded in Bracknell (Great Britain).

1963: Launch of Bisolvon^®

1963 sees the launch of Bisolvon^®, a respiratory agent developed in Biberach and the first secretolytic (mucolytic) agent resulting from the company's own research. Researchers achieve a breakthrough with the product’s further development and the active agent Ambroxol.

1965: Dr Ernst Boehringer dies

Dr Ernst Boehringer dies on 11 January aged 69. The company now employs 9,300 people worldwide and achieves sales of DM 543 million (approximately 278 million euro).

1966: Launch of Catapresan^®

1966 sees the launch of Catapresan^®, an anti-hypertensive drug with a novel mode of action.

1967: Dr Wilhelm Boehringer and Hubertus Liebrecht join Board of Managing Directors

Dr Wilhelm Boehringer and Hubertus Liebrecht, the grandsons of the company’s founder, join the Board of Managing Directors.

1969: Establishment of research unit in Japan

A new research unit is established in Kawanashi in Japan.

1971: Founding of Boehringer Ingelheim Pharmaceuticals, Inc. in Ridgefield

Boehringer Ingelheim Pharmaceuticals, Inc. Ridgefield

The foreign subsidiary Boehringer Ingelheim Pharmaceuticals, Inc. is founded in Ridgefield, Connecticut (USA), and expanded to become the company’s North American research centre.

 

1972: Launch of Berotec^®

The respiratory agent Berotec^® is launched.

1972: Founding of Boehringer Ingelheim CA in Caracas

Boehringer Ingelheim CA is founded in Caracas, Venezuela.

1972: Founding of Boehringer Ingelheim Canada Ltd. in Montreal

Boehringer Ingelheim Canada Ltd. is founded in Montreal (relocated to Burlington, Ontario, in 1978).

1972: Founding of Celamerck GmbH & Co. KG

Celamerck GmbH & Co. KG is founded in Darmstadt as a merger of Cela Ingelheim and Merck’s crop protection business. Both companies have a 50% share in the business.

1972: Lactic acid production discontinued

The production of lactic acid is discontinued.

1973: Founding of Boehringer Ingelheim GmbH

Boehringer Ingelheim GmbH is founded as the German holding company for the foreign subsidiaries in the Group.

1974: Robert Boehringer and Julius Liebrecht die

Robert Boehringer dies on 9 August.

Julius Liebrecht dies on 13 September.

1975: Launch of Atrovent^®

1975 sees the launch of Atrovent^®, a drug used in the treatment of chronic respiratory tract diseases.

1975: Dr Wilhelm Boehringer dies

Dr Wilhelm Boehringer dies on 12 January.

1976: Partnership with Geigy ends

The partnership established in 1949 with the Swiss pharmaceutical company J. R. Geigy AG at the initiative of Robert Boehringer comes to an end.

1977: Launch of Asasantin^®

1977 sees the launch of Asasantin^®, a product used in the treatment of thromboses and embolisms.

1978: Founding of Boehringer Ingelheim Vetmedica GmbH

Founding of Boehringer Ingelheim Vetmedica GmbH

1978 sees the founding of a new company, Boehringer Ingelheim Vetmedica GmbH, from the former veterinary medicine department.

 

1979: Launch of Mexitil^®

1979 sees the launch of Mexitil^®, a product used in the treatment of arrhythmia.

1979: Launch of Mucosolvan^®

1979 sees the launch of Mucosolvan^®, a product used in the treatment of bronchitis.

1980: Launch of Berodual^®

The bronchospasmolytic drug Berodual^® is launched.

1981: Founding of Boehringer Ingelheim KG

Boehringer Ingelheim KG is founded for operations in Germany.

C. H. Boehringer Sohn becomes the holding company for companies in Germany, while the newly formed Boehringer Ingelheim International GmbH becomes the holding company for companies abroad.

1982: Citric acid production discontinued

The production of citric acid is discontinued. This marks the end of Boehringer Ingelheim’s work in the area of organic acids, an area that played a key role in the company’s early economic success.

1983: Establishment of Boehringer Ingelheim Fonds (BIF)

Boehringer Ingelheim Fonds (BIF), a foundation for basic medical research, is established.

1985: Company centenary

Boehringer Ingelheim celebrates its centenary. The company now employs 22,254 people (8,784 in Germany) and achieves sales of DM 4.528 billion (approximately 2.315 billion euro).

1985: Establishment of Institute for Molecular Pathology (IMP)

The Institute for Molecular Pathology (IMP) is established in Vienna as a joint venture with Genentech, Inc. (USA). The institute opens in 1988. Since 1993, the IMP has been solely owned by Boehringer Ingelheim.

1986: New biotechnological centre in Biberach

The biotechnological centre in Biberach starts production. Following investment of around DM 150 million (approximately 77 million euro), it is Europe’s largest plant for the production of biopharmaceuticals from cell cultures.

 

 

1986: Former Minister President of Baden-Württemberg Lothar Späth (very left) visits the new biotechnological centre and is shown around by Hubertus Liebrecht (very right), a grandson of Albert Boehringer. They are joined by the chairman of the board of Thomae at the time, Dr Heinz Ried (centre).​

 

 

1987: Launch of Actilyse^®

Actilyse^®, which is used in the treatment of acute heart attacks and is the first biotech product manufactured by Thomae / Boehringer Ingelheim, is officially approved.

1987: Sale of Celamerck GmbH

Celamerck GmbH is sold.

1988: Acquisition of Bio-Méga research centre

Boehringer Ingelheim acquires the Bio-Méga research centre in Laval (Canada).